DEUBIQUITINASE JOSD1 TEMPERS HEPATIC PROTEOTOXICITY

Deubiquitinase JOSD1 tempers hepatic proteotoxicity

Abstract Derangements in protein homeostasis and associated proteotoxicity mark acute, chronic, and drug-induced hepatocellular injury.Metabolic dysfunction-associated proteasomal inhibition and the use of proteasome inhibitors often underlie such pathological hepatic proteotoxicity.In this study, we sought to identify a candidate deubiquitinating

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Risk Factors for Malfunction of Ventriculoperitoneal Shunts Performed by Medical Residents in Children: An Exploratory Study

Introduction Ventriculoperitoneal shunts (VPSs) are common neurosurgical procedures, and in educational centers, they are often performed by residents.However, shunts have high rates of malfunction due to obstruction and infection, especially in pediatric patients.Monitoring the outcomes of shunts performed by trainee neurosurgeons is important to

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BFER-Net: Babies Facial Expression Recognition Model Using ResNet12 Enabled Few-Shot Embedding Adaptation and Convolutional Block Attention Modules

The recognition of babies’ facial expressions is challenging due to the limited availability of annotated data and the complex nature of their emotions.To address this problem, this work introduces a novel dataset, FER-BYC (Facial Expression Recognition for Bangladeshi Young Children), comprising 1,425 Headphones annotated images of babies&#

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